From the late 1970s to the early 1980s, Slaughter had success in the National Wrestling Alliance, American Wrestling Association, and the World Wrestling Federation. He won the WWF Championship and headlined WrestleMania VII in 1991. Slaughter also captured the NWA United States Heavyweight Championship twice. He is a WWE Hall of Famer, inducted as part of the class of 2004. As Sgt. Slaughter, Remus became known for his dark sunglasses, his campaign hat, and his Vietnam War-era military fatigues. In the 1980s, an alternate version of the Sgt. Slaughter character was incorporated into the G.I. Joe: A Real American Hero toy line as well as its animated series and comic books.
Fictionalized versions of Sgt. Slaughter were part of the G.I. Joe: A Real American Hero toyline, animated series and comic books, as a member of the G.I. Joe team and first appeared in the five-part TV episode entitled “Arise, Serpentor, Arise!” Along with the traditional merchandising of WWE superstars, Sgt. Slaughter is one of only a few real people to be produced as a G.I. Joe figure, (NFL football player William “The Refrigerator” Perry, pro-wrestler Roddy Piper, and astronaut Buzz Aldrin are some of the others), and even appeared in G.I. Joe: The Movie.
Slaughter also appeared twice as a special guest on The Super Mario Bros. Super Show!, which starred fellow wrestler Captain Lou Albano. He appeared in the episodes “All Steamed Up” (in “Butch Mario and the Luigi Kid”) and “Caught in a Draft” (in “Bad Rap”).